- Saville Buildings
- Saw Court
- Sawyer Alley
- Sawyer's Court
- Sawyer's Yard
- Saxton's Still House
- Scaccarium
- Scalding Alley
- Scalding House
- Scalding Wick
- Scaldyng Lane
- Scallop Court
- Scavagers
- Schetebourne Lane
- Schiteburne Lane
- Schittebourne Lane
- Scholane
- Scholdynghous
- School House Passage
- Scoland
- The Scomer, Birchin Lane
- The Scorner, Houndsditch
- Scorrery's Alley
- Le Scot on the Hoop
- Scotch Hall
- Scotch Yard
- Scottish Corporation
- Scott's Wharf
- Scott's Yard
- Scouts' Hall
- Scriveners' Hall
- Scroop's Court
- Scroop's Inn
- Scrope Place
- Scrub's Court
- Scrupes Inn
- Scummer Alley
- (Soc of) Scvcia
- Seacoal Lane
- Searle's Wharf
- Second Postern
- Secondary's Office
- Sedgwick's Rents, Yard
- Sedyng Lane
- Seething Lane
- Segeryneslane
- Seintebrides Lane
- Selds
- Seleria
- Selvernestrate
- Semannescyrce, Semmanesire
- Sempringham Court
- (St.) Sepulchre
- (St.) Sepulchre's Alley
- (St.) Sepulchre's Burying Ground
- (St.) Sepulchre's Charity School
- Seremer Lane
- Serjeants' Inn, Chancery Lane
- Serjeants' Inn, Fleet Street
- Serjeants' Inn, Holborn
- Serjeants-at-Law
- Sermon Lane
- Sernes Tower
- Serpent Alley
- Sersyns Head, Snow Hill
- Sessions House, Old Bailey
- Sethod Lane
- Seuechene Lane
- Seuedenlane
- Seuehodes Lane
- Seven Star Alley, Houndsditch
- Seven Star Alley, Royal Mint Street
- Seven Star Court
- Seven Step Alley
- Seven Steps Yard
- Sevenfoot Lane
- Seyntbotulfes Lane
- The Shades
- Shaft Alley
- Shaftesbury Place
- Shaft's Court
- The Shambles
- Shareborne Lane
- Sharington House
- Sharmoneres Lane
- Sharp's Alley
- Sharp's Alley, Leadenhall Street
- Sharp's Buildings
- Sharp's Court
- Shaw's Court
- The Shearmen
- Sheen's Court
- Sheepshead, Sheepherd's Alley, Upper Thames Street
- Sheere Lane
- Sheer's Alley
- Shelles Tenement
- Shelley House
- Shepheard and Dog Alley, Shepherd and Dog Alley
- Shepheard's Court
- Shepherd and Flock Court